Acrylic acids and derivatives
Medchemexpress LLC Propanenitrile, 3-amino- | 151-18-8 | 99.99% | 70.09 | 1 G
β-Aminopropionitrile (BAPN) is a potent, specific, irreversible, and orally active inhibitor of lysyl oxidase (LOX), targeting the active site of LOX or LOXL isoenzymes. It has demonstrated the ability to normalize GLUT4 and adiponectin expression, along with improving glucose uptake in in vitro models of insulin resistance.
- Specific, irreversible, and orally active lysyl oxidase (LOX) inhibitor
- Normalizes GLUT4 and adiponectin expression
- Improves glucose uptake in insulin resistance models
- Blocks hypoxia-induced EMT morphological and marker protein changes
- Inhibits invasion and migration of cervical carcinoma cells in vitro
- Reduces body weight gain and improves metabolic profile in diet-induced obesity models in vivo
- Induces thoracic aortic dissection in C57BL/6 mice in vivo
Medchemexpress LLC β-aminopropionitrile | 10 G
β-Aminopropionitrile (BAPN) is a specific, irreversible and orally active lysyl oxidase (LOX) inhibitor. It targets the active site of LOX or LOXL isoenzymes.
- Specific, irreversible, and orally active lysyl oxidase (LOX) inhibitor.
- Targets the active site of LOX or LOXL isoenzymes.
Medchemexpress LLC HY-19816A 5mg Medchemexpress, Avitinib (maleate) CAS:1557268-88-8 Purity:>98%
Medchemexpress, HY-19816A 5mg Avitinib (maleate) CAS:1557268-88-8 Avitinib maleate is a pyrrolopyrimidine-based irreversible epidermal growth factor receptor (EGFR) inhibitor with an IC50 of 7.68 nM. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-66010 50mg Medchemexpress, Cinepazide (Maleate) CAS:26328-04-1 Purity:>98%
Medchemexpress, HY-66010 50mg Cinepazide (Maleate) CAS:26328-04-1 Cinepazide Maleate (MD-67350) is a piperazine derivative and acts as a weak calcium channel blocker. Cinepazide Maleate is a potent vasodilator and can be used for the research of cerebrovascular diseases, including ischemic stroke, brain infarct et. al. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC 3-amino-6-bromopyridine | 13534-97-9 | MFCD01646116 | 99.1% | 173.01 g/mol | C5H5BrN2 | 250 G
6-Bromopyridin-3-amine (CAS 13534-97-9) is an organic biochemical reagent used as a building block in medicinal chemistry and organic synthesis. It is supplied as a light brown to yellow solid with high chemical purity, and is suitable for use in synthetic intermediates, assay development, and other research applications.
- High chemical purity (~99.1%) suitable for research and analytical use
- Molecular formula C5H5BrN2 and molecular weight 173.01 g/mol for accurate stoichiometry
- Solid, light brown to yellow form that is easy to handle and weigh
- Available in multiple pack sizes including 250 g for scale-up needs
- Store protected from light; in solvent, -80 °C (up to 6 months) or -20 °C (up to 1 month)
eMolecules Medchem Express / Isoguvacine (hydrochloride) / 25mg / 446256124 / HY-100810 / / 68547-97-7 / MFCD00055192 / 163.600 / C6H10ClNO2
Medchem Express / Isoguvacine (hydrochloride) / 25mg / 446256124 / HY-100810 / / 68547-97-7 / MFCD00055192 / 163.600 / C6H10ClNO2
Medchemexpress LLC HY-10261A 200mg , Afatinib (dimaleate) BIBW 2992MA2;BIBW2992;Afatinib CAS:850140-73-7 Purity:98%
Medchemexpress, HY-10261A 200mg Afatinib (dimaleate) BIBW 2992MA2;BIBW2992;Afatinib CAS:850140-73-7 Formula:C32H33ClFN5O11 IC50: 0.5 nM (EGFR wt ), 0.4 nM (EGFR L858R ), 10 nM (EGFR L858R/T790M ), 14 nM (HER2) Purity:98% Afatinib dimaleate is an irreversible, dual EGFR / HER2 inhibitor, shows potent activity against wild-type and mutant forms of EGFR and HER2, with IC 50 of 0.5 nM, 0.4 nM, 10 nM and 14 nM for EGFR wt , EGFR L858R , EGFR L858R/T790M and HER2, respectively. Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Sigma Aldrich Fine Chemicals Biosciences Bisoprolol hemifumarate salt >=98% (HPLC), solid | 104344-23-2 | MFCD00792743 | 50MG
Bisoprolol hemifumarate salt >=98% (HPLC), solid | Purity: >=98% (HPLC) | Mol Wt: 383.48 | 104344-23-2 | MFCD00792743 | 50MG
eMolecules Pharmablock (2-chloropyridin-4-yl)boronic acid 250mg 551103085 PBEB0114 0 000 458532-96-2 MFCD03788416 157 360 C5H5BClNO2
Pharmablock (2-chloropyridin-4-yl)boronic acid 250mg 551103085 PBEB0114 0 000 458532-96-2 MFCD03788416 157 360 C5H5BClNO2
Medchemexpress LLC Max-40279 hemifumarate | 2388506-43-0 | 99.6% | 554.59 | C22H23FN6OS·1/2C4H4O4 | 5 MG
MAX-40279 hemifumarate is a dual, orally active small-molecule inhibitor of FLT3 and FGFR kinases, with activity against FLT3 mutants such as FLT3D835Y. It reduces NDRG1 phosphorylation at Ser330 and suppresses endothelial-to-mesenchymal transition, making it suitable for preclinical acute myelogenous leukemia research.
- Dual FLT3 and FGFR kinase inhibition.
- Orally active small-molecule profile.
- Retains activity against FLT3 mutants such as D835Y.
- Reduces NDRG1 phosphorylation at Ser330.
- Suppresses endothelial-to-mesenchymal transition (EndMT).
- High reported purity (99.6%).
- Available in small research quantities for preclinical studies.
Medchemexpress LLC 3-amino-2-chloropyridine | 6298-19-7 | MFCD00006238 | 100.0% | 128.56 | C5H5ClN2 | 100g
2-Chloropyridin-3-amine is a biochemical reagent that can be used as a biological material or organic compound for life science related research
eMolecules Orotic acid anhydrous | 65-86-1 | MFCD00006027 | 1g
Oakwood Chemical | Orotic acid anhydrous | 1g | 537710418 | 103808 | | 65-86-1 | MFCD00006027 | 156.097 | C5H4N2O4
If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link:
eMolecules Building Block Tool
Medchemexpress LLC HY-112675 100mg Medchemexpress, 4-Octyl Itaconate CAS:3133-16-2 Purity:98%
Medchemexpress,HY-112675 100mg 4-Octyl Itaconate CAS:3133-16-2 Formula:C13H22O4 4-Octyl Itaconate is a cell-permeable Itaconate derivative. Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1. Purity:98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
eMolecules 3-(2-Thienyl)acrylic acid | 1124-65-8 | 1G | Purity: 98%
Combi-Blocks | 3-(2-Thienyl)acrylic acid | 1G | 1124-65-8 | MFCD06659617 | MW:151.31
If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link:
eMolecules Building Block Tool